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Search OK Follow us: Menu Catalog Models Humanized Immune Checkpoints Single-targeted mice hPD-1 hCTLA-4 hVISTA hOX40 hGITR hLIGHT hCD28 Double-targeted mice hPD-1/hVISTA hPD-1/hCTLA-4 hCTLA-4/hLAG3 hGITR/Foxp3 Tumor cell lines MC38-hPD-L1 Immunodeficient Models BRGSF mice BRGSF-HIS mice BRGSF-A2-HIS mice Conditional Knockout Mice By therapeutic areas Cardiovascular diseases Immunology & inflammation Metabolic diseases Neuroscience Oncology models By gene families GPCR family Chemokine & cytokine models Kinases Water & ion channels Other Catalog Models Inflammation & allergy Humanized CD4 Human IgE / FcepsilonR1 Human TNF-alpha Reporter mice IL-4-IRES-eGFP (4get) Foxp3-IRES-mRFP hGITR/Foxp3 PK/PD HSA/human FcRn Rats GFP Bruton’s Tyrosine Kinase (Btk) Cell lines MC38-Pd-l1 Knockout Customized Models Customized Mouse Models Knockout mouse models Constitutive Knockouts Conditional Knockouts – Tissue-specific Knockouts – Time-dependent Knockouts Protein function Knockouts Knockin mouse models Humanized Knockins Point mutation Knockins Reporter Knockins Quick KI (Rosa26, Hprt) Conventional Knockins Customized Rat Models Constitutive Knockouts Conditional Knockouts – Tissue-specific Knockouts – Time-dependent Knockouts Point mutations Quick KI (Rosa26) Customized Cell Lines Constitutive Knockouts Point mutations Reporter Knockins Quick KI (Rosa26) Knockins Our Technologies CRISPR/Cas9 Structure Mechanism of action Efficacy Off-target activity Genetic backgrounds Knockout development Knockin development R&D programs HR Homologous recombination Typical model creations Patented procedures Obtain freedom to operate SSR Site-specific recombination Cre-ERt2: Induced Cre activity FLEx: Inducible point mutations RMCE: Gene swapping IRES Internal ribosome entry site How does it work? Multigenic disease models Reporter models Cell lineage tracking Expression pattern monitoring Cre line generation TET-On/Off On demand gene induction How does it work? About genOway Who we are From design to success License your GM model Corporate overview Careers Latest news GW & Merck strengthen alliance Extended HR license Consortium for ICP models FLEx rights granted to HHMI Merck–CRISPR/Cas9 alliance Axenis acquisition Our Clients Client portfolio Testimonials Interview Publications Publications 2018/19 Archives Commentaries Preclinical Models in I/O Nature publication on hVISTA Prime editing: New gene editing tool FLEx & Optogenetics Catalog mice: 6 good reasons why Immune checkpoint inhibitors CRISPR: Unexpected rearrangements Improving in vitro models: Organoids iPS technology: Four factors CRISPR: A Brimming Toolbox Webinar Rights to use CRISPR-based tools Optimize your syngeneic models Investors Investor relations (EN) Relations investisseurs (FR) A new strategy (EN) Une nouvelle stratégie (FR) Contact Us Thanks for reaching out. Request a quote or information Announce a meeting or invitation Careers You have been redirected to this page from www.axenis.fr genOway acquired Axenis to create the largest offer of preclinical models in the Immuno-oncology and Immuno-inflammation space. Combining both platforms and knowhow creates the largest and most comprehensive offer for target validation and assessment of biologics and cell-based therapy in both Immuno-oncology (IO) and Immuno-inflammation (I&I). In particular, it addresses Immunotherapy and its need for relevant and translatable preclinical models for the assessment of novel therapeutic approaches. Read the press release Access our immunodeficient BRGSF mouse strain portfolio Service Publications Sen NE et al. Neurobiol Dis. 2019 Dec Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation Shcherbakov D et al. Commun Biol. 2019 Oct 17 Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis > more Latest News GW & Merck strengthen alliance Extended HR license Consortium for ICP models FLEx rights granted to HHMI Merck–CRISPR/Cas9 alliance Axenis acquisition Commentaries Preclinical Models in I/O Nature publication on hVISTA Prime editing: New gene editing tool FLEx & Optogenetics Catalog mice: 6 reasons why Immune checkpoint inhibitors Interviews Interview with Prof. Donald Kuhn Applications For Models Created by Knockin For Drug Discovery Programs Therapeutic Areas Syngeneic Models Contact us Careers Site map Cookie Policy Legal Notice [© genOway 2019]

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Informations Whois

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%% [2600:3c03:0000:0000:f03c:91ff:feae:779d REQUEST] >> axenis.fr
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registrar: GANDI
type: Isp Option 1
address: 63-65 boulevard Massena
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phone: +33 1 70 37 76 61
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  REFERRER http://www.nic.fr

  REGISTRAR AFNIC

SERVERS

  SERVER fr.whois-servers.net

  ARGS axenis.fr

  PORT 43

  TYPE domain
RegrInfo
DISCLAIMER
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% short date format : DD/MM
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% Rights restricted by copyright.
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%
% Use '-h' option to obtain more information about this service.
%
% [2600:3c03:0000:0000:f03c:91ff:feae:779d REQUEST] >> axenis.fr
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  REGISTERED yes

ADMIN

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REMARKS
-------------- WARNING --------------
While the registrar knows him/her,
this person chose to restrict access
to his/her personal data. So PLEASE,
don't send emails to Ano Nymous. This
address is bogus and there is no hope
of a reply.
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  SPONSOR GANDI

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TECH

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ADDRESS
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TROUBLE
-------------------------------------------------
GANDI is an ICANN accredited registrar
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Web: http://www.gandi.net
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  ADMIN-C NL346-FRNIC

TECH-C
NL346-FRNIC
TUF1-FRNIC

  NOTIFY noc@gandi.net

  SPONSOR GANDI

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  SOURCE FRNIC

OWNER

  HANDLE ANO00-FRNIC

  TYPE PERSON

  CONTACT Ano Nymous

REMARKS
-------------- WARNING --------------
While the registrar knows him/her,
this person chose to restrict access
to his/her personal data. So PLEASE,
don't send emails to Ano Nymous. This
address is bogus and there is no hope
of a reply.
-------------- WARNING --------------

  SPONSOR GANDI

  CHANGED 2020-02-18

  ANONYMOUS YES

  OBSOLETED NO

  ELIGSTATUS not identified

  REACHSTATUS not identified

  SOURCE FRNIC

DOMAIN

  STATUS ACTIVE

  HOLD NO

  SPONSOR GANDI

  EXPIRY DATE 2021-01-28T14:30:37Z

  CREATED 2008-01-28

  CHANGED 2020-01-20

  SOURCE FRNIC

  HANDLE NSL119720-FRNIC

NSERVER

  NS-39-A.GANDI.NET 173.246.100.40

  NS-124-C.GANDI.NET 217.70.187.125

  NS-183-B.GANDI.NET 213.167.230.184

  NAME axenis.fr

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